Catalog Number - 68040-05P

Cogent NP Amino is a versatile normal phase and HILIC stationary phase designed for retention of highly polar compounds that can be difficult to retain using conventional reversed-phase columns. Manufactured on high-purity silica with a propyl amino bonded phase, it provides excellent selectivity for carbohydrates, sugars, organic acids, and other polar analytes. This stationary phase is commonly used as an alternative for USP L8 methods and is suitable for both normal phase and HILIC separations.

68040-05P is an analytical HPLC column packed with 10 µm NP Amino particles featuring a 100 Å pore size in a 4.6 mm ID x 50 mm format. The short column length is optimized for rapid analyses, fast method development, and preparative method scouting. The 10 µm particle size supports higher flow rates with lower operating backpressure, making it ideal for efficient screening and routine laboratory applications. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on mobile phase composition, analyte characteristics, and system configuration.

This column is particularly effective for sugars, carbohydrates, negatively charged compounds, carboxylic acids, organic acids, and other highly polar molecules. As an unendcapped amino phase, it is suitable for normal phase and HILIC methods where enhanced polar retention is required and is often selected as a scouting column for preparative chromatography development.

Key Benefits

• NP Amino stationary phase

• USP L8 equivalent chemistry

• Propyl amino bonded phase

• High-purity silica support

• Suitable for Normal Phase chromatography

• Suitable for HILIC applications

• Enhanced retention of polar compounds

• Excellent for sugars and carbohydrates

• Low operating backpressure with 10 µm particles

• Ideal for preparative method scouting

Typical Applications

• USP L8 methods

• HILIC separations

• Normal phase chromatography

• Sugar analysis

• Carbohydrate analysis

• Organic acid analysis

• Carboxylic acid analysis

• Food and beverage testing

• Pharmaceutical analysis

• Preparative method scouting

Specifications

• Product Type: HPLC Column

• Stationary Phase: NP Amino

• USP Classification: L8

• Chromatography Mode: Normal Phase / HILIC

• Bonded Phase: Propyl Amino

• Endcapping: Not Endcapped

• Particle Size: 10 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 50 mm

• Length: 50 mm

• Typical Flow Rate: 1.0–2.0 mL/min

• Brand: Cogent

Important Notes

• Packed and shipped in normal phase solvents

• Suitable for both normal phase and HILIC chromatographic modes

• Excellent retention of sugars, carbohydrates, and organic acids

• Short column length is ideal for rapid analyses and method development

• Frequently used as a scouting column for preparative chromatography

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